This is a list of Champions of the 1922 U.S. National Championships (now known as the US Open):
Bill Tilden defeated Bill Johnston 4-6 3-6 6-2 6-3 6-4
Molla Bjurstedt Mallory defeated Helen Wills Moody 6-3, 6-1
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| Preceded by 1921 U.S. National Championships |
U.S. National Championships | Succeeded by 1923 U.S. National Championships |
| Preceded by 1922 Wimbledon Championships |
Grand Slams | Succeeded by 1923 Australasian Championships |